Part I : This Part addresses traditional clinical research, beginning with the history of the development of clinical research, to traditional clinical research designs, with a focus on clinical trials. It includes a discussion of the role of the USFDA in clinical trials and the placebo response, data safety and monitoring boards, and meta-analysis.
Part II : This Part deals with some of the newer approaches in clinical research, specifically research methods for genetic studies, diagnostic testing studies, and pharmacoepidemiology studies. This Part concludes with a chapter that addresses a newer field of Implementation Research – that is, how to implement the research findings that are published, into everyday practice.
Part III : This Part addresses statistical concepts important for the clinical researcher. It is not a Part that is for statisticians, but rather approaches statistics from a basic foundation standpoint.
Part IV : Now that the research has been done, how is it presented? That is, how is it presented to the media and to colleagues? This Part also discusses the mentoring process that is necessary for the optimal development of a junior faculty member into an independent researcher.
Contents
Part I
1 Clinical Research: Definitions, “Anatomy and Physiology,” and the Quest for “Universal Truth”
2 Introduction to Clinical Research and Study Designs
3 Clinical Trials
4 Alternative Interventional Study Designs
5 Postmarketing Research
6 The United States Federal Drug Administration (FDA) and Clinical Research
7 The Placebo and Nocebo Effect
8 Recruitment and Retention
9 Data Safety and Monitoring Boards (DSMBs)
10 Meta-Analysis
Part II
11 Research Methods for Genetic Studies
12 Research Methods for Pharmacoepidemiology Studies
13 Implementation Research: Beyond the Traditional Randomized Controlled Trial
14 Research Methodology for Studies of Diagnostic Tests
Part III
15 Statistical Power and Sample Size: Some Fundamentals for Clinician Researchers
16 Association, Cause, and Correlation
17 Bias, Confounding, and Effect Modification
18 It’s All About Uncertainty
19 Grant Writing
Part IV
20 The Media and Clinical Research
21 Mentoring and Advising
22 Presentation Skills: How to Present Research Results
Index
List Price: $79.95
Part II : This Part deals with some of the newer approaches in clinical research, specifically research methods for genetic studies, diagnostic testing studies, and pharmacoepidemiology studies. This Part concludes with a chapter that addresses a newer field of Implementation Research – that is, how to implement the research findings that are published, into everyday practice.
Part III : This Part addresses statistical concepts important for the clinical researcher. It is not a Part that is for statisticians, but rather approaches statistics from a basic foundation standpoint.
Part IV : Now that the research has been done, how is it presented? That is, how is it presented to the media and to colleagues? This Part also discusses the mentoring process that is necessary for the optimal development of a junior faculty member into an independent researcher.
Contents
Part I
1 Clinical Research: Definitions, “Anatomy and Physiology,” and the Quest for “Universal Truth”
2 Introduction to Clinical Research and Study Designs
3 Clinical Trials
4 Alternative Interventional Study Designs
5 Postmarketing Research
6 The United States Federal Drug Administration (FDA) and Clinical Research
7 The Placebo and Nocebo Effect
8 Recruitment and Retention
9 Data Safety and Monitoring Boards (DSMBs)
10 Meta-Analysis
Part II
11 Research Methods for Genetic Studies
12 Research Methods for Pharmacoepidemiology Studies
13 Implementation Research: Beyond the Traditional Randomized Controlled Trial
14 Research Methodology for Studies of Diagnostic Tests
Part III
15 Statistical Power and Sample Size: Some Fundamentals for Clinician Researchers
16 Association, Cause, and Correlation
17 Bias, Confounding, and Effect Modification
18 It’s All About Uncertainty
19 Grant Writing
Part IV
20 The Media and Clinical Research
21 Mentoring and Advising
22 Presentation Skills: How to Present Research Results
Index
Product Details
- Hardcover: 376 pages
- Publisher: Springer; 1 edition (September 10, 2008)
- Language: English
- ISBN-10: 1402084854
- ISBN-13: 978-1402084850
- Product Dimensions: 9.3 x 6.4 x 0.8 inches
List Price: $79.95