It has been said that 80% of all medical decisions encompass clinical laboratory data in the decision process! While we know of no evidence to support this statement it is probably not far off the mark. Laboratory medicine plays an integrated role in the diagnosis, prognosis, treatment, and long-term management of disease. Proper selection and interpretation of laboratory tests is critical for quality patient care. In the last few decades, there has been an information explosion in the field of laboratory medicine, making it difficult for health care professionals to remain fluent in all aspects of laboratory testing. Applied Laboratory Medicine, Second Edition provides a comprehensive overview of modern laboratory medicine in a “real-life” case-based format. Each Case presents a patient with history and accompanying laboratory data. This is followed by discussions of how the laboratory data is used in relation to symptoms and the differential diagnosis. Most discussions also provide a definition of the disease, its pathophysiology, and treatment. We hope this book will be an excellent problem-based learning tool.
The first edition of Applied Laboratory Medicine focused primarily on traditional clinical chemistry tests. In the Second Edition, the case studies have been expanded to include hematology, coagulation, infectious disease, autoimmune disease, and molecular diagnostics. In addition, cases illustrate many new laboratory tests, new treatments, current risk factor guidelines based upon laboratory tests, and new testing algorithms. Furthermore, some examples of common laboratory problems and interferences are presented. Understanding of such interferences is paramount for proper interpretation of laboratory tests that do not fit the clinical presentation. Applied Laboratory Medicine Second Edition will be an excellent resource for medical students during their pathology course, residents, fellows, nurses, physician’s assistants, medical technologists, educators, physicians, laboratorians, and many other allied health workers.
Contents
Part One Cardiac Disease
Case 1. A 45-Year-Old Man with Substantial Chest Pain
Case 2. A 48-Year-Old Cocaine User with Chest Pain
Part Two Pulmonary Diseases
Case 3. Shortness of Breath with Productive Cough
Case 4. Genotype–Phenotype Correlations in Cystic Fibrosis
Part Three Renal Disease
Case 5. Man with Hypertension and Fever
Case 6. Oliguria with Metabolic Acidosis after Renal Transplantation
Case 7. A Woman with Uremia, Pulmonary Infiltration, and Hemoptysis
Case 8. Young Man with Edema and Decreased Urine Output
Case 9. A New Doctor for a Man with Diabetes and Hypertension
Case 10. A Pain in the Back
Case 11. Refractory Hyponatremia with Lung Cancer
Part Four Liver Diseases
Case 12. Adolescent Female with Tremor, Depression, and Hepatitis
Case 13. Adult Male with New-Onset Ascites
Case 14. An Unexpected Finding . . .:
Case 15. I Did It Just Once—A 37-Year-Old Man with Hepatitis C
Case 16. Obese Woman with Persistently Abnormal Liver Enzymes
Part Five Thyroid Diseases
Case 17. The Irritable Wife
Case 18. The Fatigued Attorney
Case 19. The Reluctant Chef
Part Six Adrenocortical Diseases
Case 20. Child with Rapid Growth and Precocious Sexual Maturation
Case 21. Weight Gain, Infertility, and Hypertension
Case 22. The Tired Teenager
Case 23. The Hypertensive Accountant
Richard D. Gordon
Case 24. Don’t “Take Two Aspirin and Call Me in the Morning”
Case 25. Unpleasant Spells
Part Seven Diabetes
Case 26. Recent Weight Loss and Polyuria in a 52-Year-Old Man
Case 27. An Unconscious Diabetic Male
Case 28. A Diabetic Woman’s “Episode”
Part Eight Calcium and Parathyroid Hormone (PTH)
Case 29. Bad to the Bone
Case 30. A Middle-Aged Woman with Colle’s Fracture
Case 31. A 10-Year-Old Boy with Pain-Induced Seizures
Part Nine Miscellaneous Endocrine Diseases
Case 32. Laboratory Tests Ignored
Case 33. Hot Flashes and Abdominal Pain
Part Ten Genetically Inherited Disorders Case 34. Feed a Cold
Case 35. Acute Neonatal Ammonia Intoxication
Case 36. Not Just a Picky Eater
Case 37. The “Fussy” Neonate
Case 38. The “Sleepy” Neonate
Case 39. A Happy but Developmentally Delayed 5-Year-Old Boy
Case 40. The Asymptomatic Iron Man
Case 41. Tired, Hot, and Lumpy
Case 42. A Rash on the Soles of the Feet
Case 43. When Life Gives You Lemons
Case 44. The Wheezing Woodsman
Case 45. Not Just Heartburn
Case 46. The Dangers of Yardwork
Case 47. An Important Finding on Routine Screening
Case 48. Increasing Abdominal Girth
Case 49. To Screen or Not to Screen?
Case 50. A Male with Confusing hCG Results
Case 51. Size Greater than Dates
Part Thirteen Hematologic Malignancies
Case 52. A Man with Anemia and Lymphocytosis
Case 53. A Teenager with Pneumonia, Leukopenia, and Ecchymoses
Case 54. A Middle-Aged Man with Chronic Foot Ulcer
Case 55. A Man with Progressive Effort Intolerance and Splenomegaly
Case 56. A Man with Splenic Vein Thrombosis and Polycythemia
Part Fourteen Benign Hematologic Disorders
Case 57. A Child with Pneumonia
Case 58. A Man with a Tender Toe and Anemia
Case 59. A Woman with Fatigue and Pallor
Case 60. Pulseless Leg 9 Days after a Myocardial Infarction
Case 61. Young Girl with a Bloody Knee Effusion
Case 62. A Young Man with Chest Pain Following a Knee Injury
Case 63. A Young Woman with Postpartum Cerebral Venous Thrombosis and Abnormal Coagulation Tests
Case 64. A Baby with Petechiae and Bruises
Case 65. Evaluation of a Reference Range Outlier
Case 66. A Woman with Abdominal
Pain and Thrombocytopenia
Case 67. Sudden Jaundice and Painful Fingers
Case 68. The Good in “Bad” Fish Tacos
Case 69. The Jaundiced Mother
Part Fifteen Porphyrias
Case 70. Young Woman with Recurrent Abdominal Pain
Case 71. A 9-Year-Old Boy with Skin Lesions and Headaches
Part Sixteen Pharmacogenomics
Case 72. Personalized Medicine for a Renal Transplant Patient
Case 73. Personalized Medicine for Pain Management
Case 74. A Man with Colitis and Pancytopenia
Case 75. A 46-Year-Old Female with a Painful, Swollen Right Calf
Part Seventeen Toxicology
Case 76. A Case of Mixed Club Drugs Abuse
Case 77. A 43-Year-Old Male with Chronic Pain
Case 78. Metabolic Acidosis of Unknown Origin Among Burn Patients
Part Eighteen Lipid Disorders
Case 79. The Family Reunion Party
Case 80. A 5-Year-Old Boy with Yellow-Orange Tonsils: Hypoalphalipoproteinemia
Case 81. Worsening Diarrhea in a 5-Year-Old Girl
Case 82. A 4-Year-Old Girl with Yellow Xanthomas and Arthritis
Part Nineteen Autoimmune Diseases
Case 83. Woman with Morning Stiffness and Tender, Swollen Joints
Case 84. Woman with a Rash and Lower Extremity Pain
Case 85. Woman with Diarrhea and Anemia
Part Twenty Analytical Errors
Case 86. Where’s My Baby?
Case 87. Elevated Concentrations, but Not Elevated Enough
Case 88. I Want To Go Home!
Case 89. Is That Really the Calcium Value?
Part Twenty-One Miscellaneous
Case 90. A Man with Fever and Acute Polyarthritis
Case 91. Middle-Aged Alcoholic with Jaundice and Ascites
Case 92. Where Did the Red Cells Go?
Index
The first edition of Applied Laboratory Medicine focused primarily on traditional clinical chemistry tests. In the Second Edition, the case studies have been expanded to include hematology, coagulation, infectious disease, autoimmune disease, and molecular diagnostics. In addition, cases illustrate many new laboratory tests, new treatments, current risk factor guidelines based upon laboratory tests, and new testing algorithms. Furthermore, some examples of common laboratory problems and interferences are presented. Understanding of such interferences is paramount for proper interpretation of laboratory tests that do not fit the clinical presentation. Applied Laboratory Medicine Second Edition will be an excellent resource for medical students during their pathology course, residents, fellows, nurses, physician’s assistants, medical technologists, educators, physicians, laboratorians, and many other allied health workers.
Contents
Part One Cardiac Disease
Case 1. A 45-Year-Old Man with Substantial Chest Pain
Case 2. A 48-Year-Old Cocaine User with Chest Pain
Part Two Pulmonary Diseases
Case 3. Shortness of Breath with Productive Cough
Case 4. Genotype–Phenotype Correlations in Cystic Fibrosis
Part Three Renal Disease
Case 5. Man with Hypertension and Fever
Case 6. Oliguria with Metabolic Acidosis after Renal Transplantation
Case 7. A Woman with Uremia, Pulmonary Infiltration, and Hemoptysis
Case 8. Young Man with Edema and Decreased Urine Output
Case 9. A New Doctor for a Man with Diabetes and Hypertension
Case 10. A Pain in the Back
Case 11. Refractory Hyponatremia with Lung Cancer
Part Four Liver Diseases
Case 12. Adolescent Female with Tremor, Depression, and Hepatitis
Case 13. Adult Male with New-Onset Ascites
Case 14. An Unexpected Finding . . .:
Case 15. I Did It Just Once—A 37-Year-Old Man with Hepatitis C
Case 16. Obese Woman with Persistently Abnormal Liver Enzymes
Part Five Thyroid Diseases
Case 17. The Irritable Wife
Case 18. The Fatigued Attorney
Case 19. The Reluctant Chef
Part Six Adrenocortical Diseases
Case 20. Child with Rapid Growth and Precocious Sexual Maturation
Case 21. Weight Gain, Infertility, and Hypertension
Case 22. The Tired Teenager
Case 23. The Hypertensive Accountant
Richard D. Gordon
Case 24. Don’t “Take Two Aspirin and Call Me in the Morning”
Case 25. Unpleasant Spells
Part Seven Diabetes
Case 26. Recent Weight Loss and Polyuria in a 52-Year-Old Man
Case 27. An Unconscious Diabetic Male
Case 28. A Diabetic Woman’s “Episode”
Part Eight Calcium and Parathyroid Hormone (PTH)
Case 29. Bad to the Bone
Case 30. A Middle-Aged Woman with Colle’s Fracture
Case 31. A 10-Year-Old Boy with Pain-Induced Seizures
Part Nine Miscellaneous Endocrine Diseases
Case 32. Laboratory Tests Ignored
Case 33. Hot Flashes and Abdominal Pain
Part Ten Genetically Inherited Disorders Case 34. Feed a Cold
Case 35. Acute Neonatal Ammonia Intoxication
Case 36. Not Just a Picky Eater
Case 37. The “Fussy” Neonate
Case 38. The “Sleepy” Neonate
Case 39. A Happy but Developmentally Delayed 5-Year-Old Boy
Case 40. The Asymptomatic Iron Man
Case 41. Tired, Hot, and Lumpy
Case 42. A Rash on the Soles of the Feet
Case 43. When Life Gives You Lemons
Case 44. The Wheezing Woodsman
Case 45. Not Just Heartburn
Case 46. The Dangers of Yardwork
Case 47. An Important Finding on Routine Screening
Case 48. Increasing Abdominal Girth
Case 49. To Screen or Not to Screen?
Case 50. A Male with Confusing hCG Results
Case 51. Size Greater than Dates
Part Thirteen Hematologic Malignancies
Case 52. A Man with Anemia and Lymphocytosis
Case 53. A Teenager with Pneumonia, Leukopenia, and Ecchymoses
Case 54. A Middle-Aged Man with Chronic Foot Ulcer
Case 55. A Man with Progressive Effort Intolerance and Splenomegaly
Case 56. A Man with Splenic Vein Thrombosis and Polycythemia
Part Fourteen Benign Hematologic Disorders
Case 57. A Child with Pneumonia
Case 58. A Man with a Tender Toe and Anemia
Case 59. A Woman with Fatigue and Pallor
Case 60. Pulseless Leg 9 Days after a Myocardial Infarction
Case 61. Young Girl with a Bloody Knee Effusion
Case 62. A Young Man with Chest Pain Following a Knee Injury
Case 63. A Young Woman with Postpartum Cerebral Venous Thrombosis and Abnormal Coagulation Tests
Case 64. A Baby with Petechiae and Bruises
Case 65. Evaluation of a Reference Range Outlier
Case 66. A Woman with Abdominal
Pain and Thrombocytopenia
Case 67. Sudden Jaundice and Painful Fingers
Case 68. The Good in “Bad” Fish Tacos
Case 69. The Jaundiced Mother
Part Fifteen Porphyrias
Case 70. Young Woman with Recurrent Abdominal Pain
Case 71. A 9-Year-Old Boy with Skin Lesions and Headaches
Part Sixteen Pharmacogenomics
Case 72. Personalized Medicine for a Renal Transplant Patient
Case 73. Personalized Medicine for Pain Management
Case 74. A Man with Colitis and Pancytopenia
Case 75. A 46-Year-Old Female with a Painful, Swollen Right Calf
Part Seventeen Toxicology
Case 76. A Case of Mixed Club Drugs Abuse
Case 77. A 43-Year-Old Male with Chronic Pain
Case 78. Metabolic Acidosis of Unknown Origin Among Burn Patients
Part Eighteen Lipid Disorders
Case 79. The Family Reunion Party
Case 80. A 5-Year-Old Boy with Yellow-Orange Tonsils: Hypoalphalipoproteinemia
Case 81. Worsening Diarrhea in a 5-Year-Old Girl
Case 82. A 4-Year-Old Girl with Yellow Xanthomas and Arthritis
Part Nineteen Autoimmune Diseases
Case 83. Woman with Morning Stiffness and Tender, Swollen Joints
Case 84. Woman with a Rash and Lower Extremity Pain
Case 85. Woman with Diarrhea and Anemia
Part Twenty Analytical Errors
Case 86. Where’s My Baby?
Case 87. Elevated Concentrations, but Not Elevated Enough
Case 88. I Want To Go Home!
Case 89. Is That Really the Calcium Value?
Part Twenty-One Miscellaneous
Case 90. A Man with Fever and Acute Polyarthritis
Case 91. Middle-Aged Alcoholic with Jaundice and Ascites
Case 92. Where Did the Red Cells Go?
Index
Book Details
- Paperback: 704 pages
- Publisher: Wiley-Liss; 2 edition
- Language: English
- ISBN-10: 0471714577
- ISBN-13: 978-0471714576
- Product Dimensions: 9.7 x 6.8 x 1.4 inches